Ganga Social Foundation, being a responsible NGO, has partnered too with State Aids Control Societies (SACS) of different states to work for prevention of HIV/AIDs and STIs through Targeted Intervention (TI) Program and successfully running the TI Program since 2010. The first partnership for TI Program was done with Delhi State AIDS Control Society (DSACS) in the year 2010. Further GSF has been able to partner with Haryana State Aids Control Society (HSACS) in 2011 and Punjab State Aids Control Society (PSACS) in 2014 because of the recommendation for its good work with DSACS.

Targeted intervention is a very significant component of National AIDS Control Programme (NACP). These interventions provide an opportunity to provide comprehensive and integrated HIV prevention as well as care and support services to extremely marginalized High-Risk Groups, such as Female Sex Workers (FSWs), Men who have Sex with Men (MSMs), People Who Inject Drugs (PWID) and also to bridge populations like Migrant workers and long-distance Truckers.